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Closure of the atrial appendage was superior to oral anticoagulation in safety and noninferior in effectiveness.

In this randomized trial, peripherally inserted central catheters made with novel materials did not have lower failure rates than conventional polyurethane PICCs.

Hip fractures were 30% more common among older people who were taking gabapentinoids.

Two reports suggest that a daily trial, as opposed to several in a day, is better.

In this observational study, GLP-1 receptor agonists were associated with lower risk for AUD hospitalization.

A meta-analysis of 12 studies of early versus late initiation of norepinephrine demonstrated similar mortality and intensive care unit length of stay.

Chest discomfort and complications did not differ between the two methods.

Mucus plugs seen on chest CT in patients without evident symptoms were associated with more-severe disease.

The data are relatively convincing for hypoxemic respiratory failure but are less so for COPD exacerbations with hypercarbia.

In a randomized trial, lowering systolic BP to ≈120 mm Hg resulted in fewer strokes.