Intensive vs. Standard Blood Pressure Lowering in Patients with Diabetes Description In a randomized trial, lowering systolic BP to ≈120 mm Hg resulted in fewer strokes.
Is “As-Needed” Blood Pressure Medication Really Needed in Inpatients? Description Treating inpatients who had asymptomatic BP elevations was associated with risk for acute kidney injury, myocardial infarction, stroke, or death.
Guidelines for the Primary Prevention of Stroke Description This is the first major update to these guidelines since 2014.
How Do the Two Available Single-Inhaler Triple Therapies for COPD Compare? Description An observational study suggests some small differences in outcomes.
Can Tracking Inflammatory Biomarkers Shorten Antibiotic Duration in Patients with Sepsis? Description Measuring procalcitonin shortened antibiotic duration by about 1 day, but questions about safety remain.
How Is Cancer Managed at the End of Life? Description Some oncologists are far more aggressive than others.
Is Accelerated Surgery for Hip Fracture Better for High-Risk Patients? Description In patients with hip fracture and an elevated troponin level, rapid surgical intervention was associated with lower mortality.
Should Urea Be Used for Managing SIADH? Description A recent meta-analysis suggests that it is safe and effective for syndrome of inappropriate antidiuretic hormone secretion.
Tirzepatide in Patients with Obesity and Prediabetes Description During a 3-year study, most patients reverted to normoglycemia.
Anticoagulation During Hospitalization for COVID-19 Description A meta-analysis reaffirms generally better outcomes with therapeutic than with prophylactic anticoagulation — with some exceptions.